An Employee Is Diverting Drugs: Who You Must Tell, and When
When an investigation points to an employee, the reports you owe depend on what was lost, where you are and what license the employee holds. Some deadlines are federal and fixed. Others are set by your state or the employee's licensing board, and they differ.
The short answer
The federal report is about the drugs, not the person. If there was a theft or significant loss, the DEA must be told in writing within one business day of discovery, whether or not you know who took them. Reports about the employee, to a licensing board or the police, are set by state law and by the board that licensed them, and they differ from state to state and between professions.
Who may need to be told
| Who | When | Set by |
|---|---|---|
| DEA Field Division Office | Theft or significant loss: in writing “within one business day of discovery”, then a complete DEA Form 106 “within 45 days after discovery”. | 21 CFR 1301.76(b) |
| Pharmacy director and CEO (hospitals) | “Abuses and losses of controlled substances must be reported, in accordance with applicable Federal and State laws, to the individual responsible for the pharmaceutical service, and to the chief executive officer, as appropriate.” | 42 CFR 482.25(b)(7) |
| State board of pharmacy | Thefts and losses, under the state's own rules and deadline, which can be shorter or broader than DEA's. | State pharmacy law. Varies by state. |
| The employee's licensing board | Whether an employer must report a nurse, pharmacist, technician or physician, and how fast, depends on the state and the profession. In some states it is mandatory; elsewhere it may be left to judgment. | State law and that board's rules. Varies by state and profession. |
| Law enforcement | The federal rules cited here do not require a police report. Whether to make one is a decision for leadership and counsel, under any state rule that applies. | Your policy and counsel. |
| Patients | If tampering or substitution may have affected care or exposed patients to infection. | See patient notification after drug diversion. |
Your registration, license and accreditation may each add obligations. Check them for your own facility rather than relying on this table alone.
Do not wait for the investigation to finish
The one-business-day clock runs from discovery of the theft or loss, not from the end of your investigation or the employee's interview. There is no fixed quantity that makes a loss significant. The regulation lists factors to weigh, including the quantity in relation to the type of business, the specific drug, “whether the loss of the controlled substances can be associated with access to those controlled substances by specific individuals”, and any pattern of losses over time (21 CFR 1301.76(b)). If the loss can be tied to one employee, that is itself one of the factors.
The DEA Form 106 guide covers what goes on the form.
Reports from staff, inside the organization
Most concerns start with a colleague. DEA has stated its position that “an employee who has knowledge of drug diversion from his employer by a fellow employee has an obligation to report such information to a responsible security official of the employer”, and that the employer “shall take all reasonable steps to protect the confidentiality of the information and the identity of the employee furnishing information” (21 CFR 1301.91).
That section sits under the heading “Employee Screening—Non-Practitioners”, which covers registrants such as distributors, not hospitals or pharmacies. Do not cite it as a rule that binds a hospital or pharmacy. It is still a sound model for your own policy: tell staff they must report, tell them to whom, and protect the person who does. For the staff-side steps, see how to report drug diversion.
When the employee reports themselves
Some diversion comes to light because the employee discloses a substance use problem. Many states have an alternative-to-discipline or peer assistance program for licensed professionals. Who is eligible, whether a self-report changes what the employer must report, and what the board is told all depend on the state and the profession. Ask the licensing board or the program directly, and check with counsel before telling the employee what will happen. A self-report does not remove the DEA report if drugs were lost.
Keep a record of every report
For each report, keep the date and time it was made, who made it, who received it, what it said, and any reply or reference number. When an inspector or a board asks whether a loss was reported on time, this is the record that answers.
Sources
Read on October 16, 2026. Educational content, not legal advice; check your state's current rules and your licensing boards' rules before relying on a deadline.
Further reading
Reporting the loss
The one-business-day notice and the Form 106.
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DEA Form 106 vs. Preliminary Notification: The 1-Business-Day Rule Explained
The two-step reporting framework for theft or significant loss of controlled substances — and why the one-business-day rule matters.
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How to File DEA Form 106: A Step-by-Step Guide for Pharmacies
When to file, the one-business-day preliminary notification rule, the 45-day deadline, and how to complete the form without common mistakes.
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How to Report Drug Diversion: A Step-by-Step Guide for Healthcare Staff
Who to tell, what to document, and when a report must reach the DEA — a practical reporting guide for pharmacy staff, nurses, and compliance officers.
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DEA 106 Filing Guide
When to file, step-by-step form completion, common mistakes, and sample scenarios
Investigating the employee
Gathering the evidence and interviewing fairly.
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Investigation Playbook
Step-by-step guide from initial report through resolution and corrective action
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Interview Guide
Preparation, questioning techniques, documentation standards, and legal considerations
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Patient Notification After Drug Diversion
When and how to notify patients potentially exposed through drug diversion, with bloodborne pathogen testing guidance
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Employee Screening & Fitness for Duty
Pre-employment vetting, DEA screening requirements, and ongoing fitness-for-duty monitoring for staff with controlled substance access
Other topics
Check your reporting and investigation process
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